HanhanXie

Research direction:two-dimensional nanomaterials, biomedical materials, tumor-targeted cancer therapy

Postbox:xiehh@sustech.edu.cn

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Hanhan Xie, Research Assistant Professor, Master Tutor (Associate Researcher)
Hanhan Xie is a research assistant professor in the Department of Mechanical and Energy Engineering, Southern University of Science and Technology. She received Ph.D. degree from Wuhan University in 2018. From 2018 to 2021, she worked as a postdoctoral researcher in Shenzhen People's Hospital, and as a visiting postdoctoral fellow at the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences. In April 2021, she joined the Department of Mechanical and Energy Engineering of Southern University of Science and Technology as a research assistant professor. Her main research directions are two-dimensional nanomaterials and their applications in the field of biomedicine. In recent years, she has published more than 20 SCI papers, the h-index is 16, and cited more than 2,700 times. Among them, she has published 9 SCI papers in Angewandte Chemie International Edition, Small, Biomaterials, ACS Applied Materials & Interfaces and other international authoritative journals as the first author or co-first author. Among them, three of the papers are selected as the "cover story". Moreover, she has applied for 8 Chinese invention patents, 4 have been authorized. Besides, she has hosted and participated in 4 scientific research projects including the National Natural Science Foundation of China and the China Postdoctoral Science Foundation.

Educational experience:
◆2013.09-2018.06 Wuhan University, Ph.D ◆2014.10-2018.06 Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Visiting student
◆2009.09-2013.06 Anqing Normal University, Bachelor

Work experience:
◆2021.04.08-now, Southern University of Science and Technology, Research Assistant Professor, ◆2018.07-2021.03 Shenzhen People's Hospital, Postdoctoral
◆2018.07-2021.03 Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Visiting postdoctoral fellow

Personal honor:
(1) Shenzhen high-level talents (reserve level), 2021.06
(2) Special Award for the Dean of Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2015.09

Representative papers:
[1] HH Xie, MQ Liu, BH You, GH Luo, Y Chen, BL Liu, ZY Jiang, PK Chu, JD Shao, and XF Yu. Biodegradable Bi₂O₂Se Quantum Dots for Photoacoustic Imaging-Guided Cancer Photothermal Therapy. Small, 2020, 16, 1905208.
[2] HH Xie, PH Li, JD Shao, H Huang, Y Chen, ZY Jiang, PK Chu, XF Yu. Electrostatic Self-Assembly of Ti₃C₂T_xMXene and Gold Nanorods as an Efficient Surface-Enhanced Raman Scattering Platform for Reliable and High-Sensitivity Determination of Organic Pollutants. ACS Sensors, 2019, 4: 2303-2310.
[3] HH Xie^#, JD Shao^#, YF Ma^#, JH Wang, H Huang, N Yang, HY Wang, CS Ruan, YF Luo, QQ Wang, PK Chu, XF Yu. Biodegradable near-infrared-photoresponsive shape memory implants based on black phosphorus nanofillers. Biomaterials, 2018, 164: 11-21.
[4] JD Shao^#, HH Xie^#, HY Wang, WH Zhou, Q Luo, XF Yu, PK Chu. 2D Material-Based Nanofibrous Membrane for Photothermal Cancer Therapy. ACS Applied Materials & Interfaces, 2018, 10: 1155-1163.
[5] HH Xie, JD Shao, JH Wang, ZB Sun, XF Yu, QQ Wang. Near-infrared optical performances of two Bi₂Se₃ nanosheets. RSC Advances, 2017, 7: 50234-50238.
[6] HH Xie, ZB Li, ZB Sun, JD Shao, XF Yu, ZN Guo, JH Wang, QL Xiao, HY Wang, QQ Wang, H Zhang, PK Chu. Metabolizable ultrathin Bi2Se3 nanosheets in imaging-guided photothermal therapy. Small, 2016, 12: 4136-4145.
[7] ZB Sun^#, HH Xie^#, SY Tang, XF Yu, ZN Guo, JD Shao, H Zhang, H Huang, HY Wang, PK Chu. Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents. Angewandte Chemie International Edition, 2015, 54: 11526-11530.
[8] HH Xie, Q Wen, H Huang, TY Sun, PH Li, Y Li, XF Yu, QQ Wang. Synthesis of bright upconversion submicrocrystals for high-contrast imaging of latent-fingerprints with cyanoacrylate fuming. RSC Advances, 2015, 5: 79525-79531.
[9] HH Xie, M Wu, H Huang, F Qi, L Gu, HY Zhu, XF Yu, QY Gong. Facile Synthesis of Multifunctional Nanocomposites with Magnetic/Upconversion Fluorescence and Singlet Oxygen Generating Capacity. Nanoscience and Nanotechnology Letters, 2015, 7: 375-380.
[10] JD Shao, CS Ruan, HH Xie, PK. Chu, XF Yu. Photochemical Activity of Black Phosphorus for Near‐Infrared Light Controlled In Situ Biomineralization. Advanced Science, 2020, 7, 2000439.
[11] YH Kang, HH Xie, DN Liu, M. Gao, PK Chu, S Ramakrishna, XF Yu. Facile mass production of self-supported two-dimensional transition metal oxides for catalytic applications. Chemical Communications, 2019, 55: 11406-11409.
[12] JD Shao, CS Ruan, HH Xie, ZB Li, HY Wang, PK Chu, XF Yu. Black-Phosphorus-Incorporated Hydrogel as a Sprayable and Biodegradable Photothermal Platform for Postsurgical Treatment of Cancer. Advanced Science, 2018, 5:1700848.
[13] XZ Wang, JD Shao, MAE Raouf, HH Xie, H Huang, HY Wang, PK Chu, XF Yu, Y Yang, ABM AbdEl-Aal, NHM Mekkawy, RJ Miron, YF Zhang. Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration. Biomaterials, 2018,179: 164.
[14] ZH Song, YZ Chang, HH Xie, XF Yu, PK Chu, TF Chen. Decorated ultrathin bismuth selenide nanosheets as targeted theranostic agents for in vivo imaging guided cancer radiation therapy. NPG Asia Materials, 2017, 9: e439.
[15] ZB Li, JD Shao, Q Luo, XF Yu, HH Xie, HD Fu, SY Tang, HY Wang, GL Han, PK Chu. Cell-Borne 2D Nanomaterials for Efficient Cancer Targeting and Photothermal Therapy. Biomaterials, 2017, 133: 37-48.
[16] HD Fu, ZB Li, HH Xie, ZB Sun, BK Wang, H Huang, GL Han, HY Wang, PK Chu, XF Yu. Different-sized black phosphorus nanosheets with good cytocompatibility and high photothermal performance. RSC Advances, 2017, 7: 14618.
[17] XH Li, RK Liu, HH Xie, Y Zhang, B Lyu, P Wang, JH Wang, Q Fan, Y Ma, SH Tao, S Xiao, XF Yu, YL Gao, J He. Tri-phase all-optical switching and broadband nonlinear optical response in Bi2Se3 nanosheets. Optics Express, 2017, 25: 18346-18354.
[18] YH Xu, HH Xie, GB Jiang, LL Miao, K Wang, SY Tang, XF Yu, H Zhang, QL Bao. Bilayer Bismuth Selenide nanoplatelets based saturable absorber for ultra-short pulse generation. Optics Communications, 2017, 395：55-60.
[19] JD Shao, HH Xie, H Huang, ZB Li, ZB Sun, YH Xu, QL Xiao, XF Yu, YT Zhao, H Zhang, HY Wang, PK Chu. Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy. Nature Communications, 2016, 7: 12967.
[20] Y Yang, J Gao, Z Zhang, S Xiao, HH Xie, ZB Sun, JH Wang, CH Zhou, YW Wang, XY Guo, PK Chu, XF Yu. Black Phosphorus Based Photocathodes in Wideband Bifacial Dye-Sensitized Solar Cells. Advanced Materials, 2016, 28: 8937-8944.
[21] YT Zhao, HY Wang, H Huang, QL Xiao, YH Xu, ZN Guo, HH Xie, JD Shao, ZB Sun, WJ Han, XF Yu, PH Li, PK Chu. Surface Coordination of Black Phosphorus for Excellent Air and Water Stability, Angewandte Chemie International Edition, 2016, 128: 5087-5091.
[22] SY Tang, ZN Guo, JD Shao, XF Yu, HH Xie, Y Li, PH Li, L Zhang, RKY Fu, HY Wang, PK Chu. Drawing-fabrication of multifarious nanoplasmonic platform on PLLA paper for optimized SERS performance. Journal of Raman Spectroscopy, 2016, 14: 687-691.
[23] ZN Guo, H Zhang, SB Lu, ZT Wang, SY Tang, JD Shao, ZB Sun, HH Xie, HY Wang, XF Yu, PK Chu. From Black Phosphorus to Phosphorene: Basic Solvent Exfoliation, Evolution of Raman Scattering, and Applications to Ultrafast Photonics. Advanced Functional Materials, 2015, 25: 6996-7002.
[24] H Huang, JH Wang, WH Jin, PH Li, M Chen, HH Xie, XF Yu, HY Wang, ZG Dai, XH Xiao, PK Chu. Competitive Reaction Pathway for Site-Selective Conjugation of Raman Dyes to Hotspots on Gold Nanorods for Greatly Enhanced SERS Performance. Small, 2014, 10: 4012-4019.